A U.N. convoy of about 80 trucks is ready to cross the Turkish border into Syria for the first time, aid officials said on Wednesday.

A U.N. convoy of about 80 trucks is ready to cross the Turkish border into Syria for the first time, aid officials said on Wednesday, in a step they hope will pave the way for humanitarian access to the country's most desperate areas, World Bulletin website reported.

The convoy became possible after the U.N. Security Council last month unanimously called on Syrian authorities and armed groups to allow prompt access for humanitarian supplies across front lines and borders by the most direct routes.

Last week, Syria granted its approval to the opening of the border crossing, and sources said Turkey had also now given the delivery the go-ahead.

However, one Western official said the convoy would not reach some of the areas worst affected by the conflict, which has killed more than 140,000 people, driven 2.5 million to seek refuge abroad and displaced a total of 9 million.

"This is a significant step because it is the first U.N. convoy going across from Turkey into Syria since the conflict started," a senior aid official told Reuters.

The official added that non-governmental organizations had already been using Turkey's Nusaybin border post close to the Kurdish city of Qamishli inside Syria "for years" to convey smaller consignments of aid.

"Obviously we need more access," the official added.

Officials said the U.N. aid delivery was expected to take place soon but declined to give a precise timeframe.

"There will be U.N. organizations like UNHCR, UNICEF and maybe one or two others within that," a Turkish official said, referring to the U.N.'s refugee and children's agencies.

Charities such as Save the Children have complained that the Feb. 22 U.N. Security Council resolution has not curbed Syria's suffering and say many sides in the conflict are failing to meet their obligations set out in the U.N. text.