The Vatican’s first accord with the Palestinians came into force on Saturday after being attacked by the Zionist entity as counter-productive to the Middle East peace process.

The Vatican's first accord with the Palestinians came into force on Saturday after being attacked by the Zionist entity as counter-productive to the Middle East peace process, the Holy See announced.

The accord was signed in June, just over two years after the Roman Catholic Church recognized the Palestinian territories as a sovereign state in February 2013.

The accord covers the operation of the Church in areas of the Holy Land under Palestinian control but its significance has been seen in broader terms as a symbol of growing international backing for a Palestinian state.

"With reference to the Comprehensive Agreement between the Holy See and the State of Palestine, signed on 26 June 2015, the Holy See and the State of Palestine have notified each other that the procedural requirements for its entry into force have been fulfilled," a Vatican statement said.

"The agreement... regards essential aspects of the life and activity of the Church in Palestine, while at the same time reaffirming the support for a negotiated and peaceful solution to the conflict in the region."

In June, the Vatican hailed the agreement, which includes provisions to protect the rights of Christians, as a model for other Arab and Muslim states in their relations with Christian minorities facing increasing persecution in the Middle East.

The Vatican's recognition of the state of Palestine -- joining dozens of others -- followed a November 2012 vote in favor of recognition by the UN General Assembly.